Nutrigenomics: Advancing Personalized Medicine - Part 2

Written by Anil Bajnath, MD
Posted December 29, 2020

Dear Reader,

The study of nutrigenomics is helping us visualize and understand the subtle, yet the profound, connection between our genetic blueprint and the food and nutrients we put into our bodies...

Last week, I'd mentioned that there are many genetic tests folks could take. But they’re often not personalized to the level that they should be. They are limited in what they can provide to customers legally, and their reporting is incomplete and broad...

So here's something to consider...

What can the testing tell me?

Dr. Mark Hyman is known for using the phrase, “Genetics loads the gun, but lifestyle/environment pulls the trigger.” Our genes aren’t our destiny. The choices we make can determine how they are expressed. Even if we’re predisposed to a specific disease, we can potentially stop that from becoming reality by looking at SNPs and the specific pathways they affect.

In a 2007 research review, two doctors concluded that, “Effects of genetic diseases previously considered untreatable may now be ameliorated by administering higher amounts of the coenzyme(s) required for more efficient metabolic function. Through genetic and functional testing . . . risk factors may be identified and truly personalized interventions to improve health designed.”

The Institute for Human Optimization uses a test called GenomicInsight®, which combines today’s most advanced DNA testing with the powerful Opus23 Explorer® interface to produce the perfect combination of DNA testing, science, and current research.

Opus23 Explorer® scans over 20 peer-reviewed, evidence-based scientific databases, including metabolic pathways, etiological associations, and pharmacogenomic databases, and cross-references their information with the results of your GenomicInsight® raw data. This report summarizes important findings from your genomic data that will be curated by your clinical team into an easy-to-understand format.

How can The Institute for Human Optimization help me?

Using Opus23 Explorer® requires a highly-trained and specialized clinician to interpret and curate the data for the patient. Our clinicians will put your data in the appropriate context, taking into account your medical history, your stressors, your diet, your lifestyle, and so forth. So much data is available through this incredible analysis platform that your information will constantly be updated like a living document, as new research is done, new literature is published, and new discoveries are made.

Opus23 Explorer® assesses over 900,000 SNPs, but we only focus on 6,000 or so that have been clinically curated and shown to have an impact on disease progression and quality of life. Based on your genomic data, the platform allows our clinicians to assess the efficacy of natural products and foods that may be worthy of attention as potentially valuable therapeutic agents. The platform uses a combination of evidence-based medicine and your genomics to compile the most clinically applicable data that makes nutritional recommendations specific to YOU.

There is also another level to our testing that adds on microbiome analysis and integrates it with your genomic data. Previously, we mentioned that your microbiome regulates 99% of your gene expression! The test will tell us how your body is integrating your lifestyle and environment with the genetic blueprint you were born with, and make recommendations accordingly!

The promise of precision medicine begins with your story. We provide the most comprehensive, data-driven approach to wellness. It is:

  • Predictive – We use genomics and advanced biomarker testing for risk stratification and empowerment.
  • Personalized – We use data-driven health information to curate actionable change for disease mitigation and prevention.
  • Preventive – We utilize highly individualized programs tailored to your unique genomic blueprint.
  • Participatory – We empower engagement in personal choices, which allows for improved outcomes and enhanced results.

Let’s discover your personalized nutrition plan together!

To your longevity,

Anil Bajnath MD
CEO/Founder, Institute for Human Optimization
Chief Medical Advisor, Longevity Insider HQ

* This content is provided by the Institute for Human Optimization (