Metabolomics: Bridging the Gap From Genotype to Phenotype – Part 2

Written by Anil Bajnath, MD
Posted May 27, 2021

Dear Longevity Insider,

I recently shared with you the importance of metabolomics.

I explained how omics research is currently exploring how genetic effects on phenotype are being filtered through the metabolome, making it a critical omic to possibly bridge the gap between genotype and phenotype.

This will be a powerful tool in informed decision making, developing drugs, and preventative healthcare.

Uses Today & Future Applications

Precision Nutrition: Metabolomics has emerging applications with precision nutrition which has the goal of customized nutritional recommendations. Utilizing metabolomics data, researchers can make better nutritional recommendations.  For example,  utilizing metabolomic data, when we look at infant formula, it has been optimally formulated to mimic the molecular composition of human milk taking into account the distribution of fatty acids. 

Dietary Analysis: Researchers are using metabolites found in blood and urine to accurately measure dietary intake. This is a gateway to assess eating habits as currently the tools being used rely on our recordation and subject to human error.

Biomarker Discovery: Human metabolites being profiled has accelerated biomarker discovery.

Future of Medicine

Utilizing Omics data will provide us the lens for the molecular microscope to objectively examine individual variability. With metabolomics being used to identify metabolites that alter a phenotype, it is no surprise that many researchers consider metabolomics as the omics discipline closest to the phenotype.

The future of medicine is a precision-based medicine approach that takes into account your bio-individuality, environment, lifestyle, and molecular phenotype to find the best clinical care option for you. The Institute for Human Optimization is committed to helping you create a personalized plan for living your longest, healthiest life possible. My team and I leverage the most cutting-edge advances in genetic testing, nutritional analysis, and functional medicine to get to the root biological imbalances that cause aging.

We know that each person is truly unique. From DNA to iris, we all possess a blueprint that is genetically inherited and environmentally influenced. By gaining a deeper appreciation for the person on a molecular level and addressing the root causes driving disease, we can help promote optimized health through our unique scientific, N of 1, approach to individualized care.

And of all of my research, I've located the #1 cause for early aging.

Check it out.

To your longevity,

Anil Bajnath MD
CEO/Founder, Institute for Human Optimization
Chief Medical Officer, Longevity Insider HQ