Feeling bloated or constipated? The likely culprit – Part 1

Written by Anil Bajnath, MD
Posted September 14, 2021

Dear Longevity Insider,

Studies show that up to 70% of people with unexplained chronic digestive issues have small intestinal bacterial overgrowth (SIBO).

SIBO is defined as an increase in the number and/or alteration in the type of bacteria in the upper gastrointestinal tract. SIBO is a condition in which abnormally large numbers of bacteria grow in the small intestine. SIBO is considered a gut microbiome disorder. Normally, there are a small number of bacteria present in the small intestine. This balance becomes upset due to a poor diet, or certain health conditions such as chronic pancreatitis, Crohn's disease, ulcerative colitis and more. While symptoms vary, they generally include bloating and gas in the stomach and intestines, diarrhea and constipation alternating with periods of normal bowel movements, abdominal cramping or pain without any other identifiable cause. The small intestine is responsible for absorption of all nutrients from food, including proteins, carbohydrates (sugars), fats (lipids), and vitamins. SIBO causes malabsorption of these nutrients. SIBO contributes to an increased risk for malnutrition, especially vitamin B12 deficiency (because of the ileum's inability to absorb) and vitamin D deficiency (due to decreased exposure of SIBO-induced malabsorption). SIBO can also cause deficiencies in iron, calcium, magnesium, and more.


SIBO is caused by the overgrowth of the bacteria in the small intestine. The small intestine has substantially less microorganisms than the large intestine. When bacteria that belongs in the large intestine is found present in the small intestine, this disrupts the synergism of bacteria and SIBO occurs. SIBO is thought to be caused by an abnormally accelerated transit rate of intestinal contents through the small intestine. SIBO can increase fermentation of carbohydrates, leading to uncomfortable symptoms including gas, bloating, and a distended abdomen after you eat a meal. This increase in number can be due to a variety of factors, including:
  • Cirrhosis of the liver.
  • Autoimmune conditions.
  • Celiac disease and other gastrointestinal disorders.
  • Low stomach acid.
  • Use of certain medications such as: narcotics, antacids containing magnesium, proton pump inhibitors, diabetes medications, antibiotics and more.
  • Dietary causes such as: carbohydrate overload, excessive sugar intake and artificial sweeteners.
  • And much more!

In SIBO, the bacterial overgrowth is typically not very big in size... On Thursday, I'll reveal more on how SIBO manifests in the body in a rather sneaky way. 

Something else sneaky, could be happening in your body right now. It's called cellular senescence, and it leaves the body riddled with "zombie cells." These cells often leave people feeling sick, fat, moody, tired, and downright old.

But numerous clinical studies support a process called autophagy, which helps to clean the body of these toxic zombie cells.

Do you have zombie cells in your body?

Are they contributing to your accelerated aging?

Here's my most-prized research on zombie cells and autophagy.

I've received hundreds of notes from people who say my research has impacted their life for the better.

Don't wait. Take a look at my presentation right now.

To your longevity,

Anil Bajnath MD
CEO/Founder, Institute for Human Optimization
Chief Medical Officer, Longevity Insider HQ