Colorado Scientists Discover How to Make Old Blood New Again?

Written by Alex Reid
Posted March 15, 2021

Hi y’all!

Alex Reid here with your Monday roundup.

Red blood cells make up 90% of your body's cells. And every day, your body produces over 200 billion more of them. After all, you need every last one... They help to transport oxygen and even help control infection in the body.

The problem is that red blood cells have a short lifespan of just 120 days. This is why the body is always in overdrive kicking out more every day.

But as aging settles in, this blood-cell-producing process becomes hard for your body to keep up with. And without enough healthy, fresh red blood cells, you could experience health problems, ranging from anemia to blood cancers.

Instead of just accepting the “inevitable,” a group of experts at the University of Colorado Anschutz Medical Campus has discovered a way to keep the body pumping out new red blood cells.

Angelo D’Alessandro, PhD, ‒ an expert in blood cell research at the University of Colorado School of Medicine ‒ likens the concept to changing the oil in a car:

If we manage to keep 90% of the cells in our body young, chances are that much of our body is going to be young.

Here’s the gist of how the body is able to generate so many red blood cells on a daily basis (in D’Alessandro’s words):

This fascinating phenomenon is made possible by the capacity of hematopoietic stem cells (HSCs) to multiply and differentiate into all the blood cell types, a mechanism that unfortunately can become impaired as we get old. Results can include anemia, when we can’t make enough red blood cells, or blood cancers, when some blood cell precursors go rogue and start multiplying without differentiating.

And in an attempt to fight back against aging, the researchers targeted something called chaperone-mediated autophagy (CMA). CMA is usually responsible for clearing the body of damaged proteins and wastes.

But with aging, this natural phenomenon can start to fail at its job. This sabotages those HSCs that D’Alessandro mentioned, inevitably leading to blood health complications.

But here’s one protein these scientists believe can change it all.

To your health,

Alex Reid
President, Longevity Insider HQ

P.S. Our very own Chief Medical Officer, Dr. Anil Bajnath, has pinned down the #1 cause of early aging. Watch here.