Biomarkers: Connecting the Molecular Dots - Part 1

Written by Anil Bajnath, MD
Posted November 12, 2020

Dear Reader,

We’ve talked about how your story begins with the fact that DNA determines an overwhelming amount of information about who you are, what you look like, and how certain environmental factors influence your overall health. We’ve also talked about how the state of your microbiome, which is the important and complex social network of microorganisms that coinhabit your body, contributes to the development of a strong immune system and your overall wellness.

Let’s continue to connect the molecular dots of your life story.

At The Institute for Human Optimization, understanding your story is a critical element in our approach to your healthcare. Genomic testing enlightens your predisposition to certain health vulnerabilities. Microbiome testing shines the light on how microbial imbalances in your body manifest in illness and disease. And last but definitely not least, comprehensive biomarker testing gives you a snapshot of your current state of health. This enables us to take a deep dive into your story and translate your unique book of life. We gain insights about you individually, and we learn how we can leverage this information to help influence clinical decision making.

Biomarkers, portmanteau for “biological markers,” are measurable substances, usually proteins encoded by DNA, which provide useful information about medical conditions or disease processes. They are found in blood, urine, saliva and various tissues.  They help establish a baseline health status, serve as an early warning sign of potential health concerns, and provide objective goals which can be clinically monitored and used to track your progress.

There are two main ways of assessing biomarker ranges.

The pathological range is used to diagnose disease. Typical reference ranges provided with laboratory testing results are reported in “pathological ranges.” They are generated in reference to all available laboratory results. These usually reflect any number out of this range as having an underlying potential disease process, and see the disease diagnosis as an endpoint in care.

The functional range is used to assess risk for disease before it develops. The Institute for Human Optimization uses this information to help identify and prevent specific conditions using a proactive, preventative approach. We not only asses your basic, conventional biomarker standards, but we take it a step further towards health optimization and disease prevention. Jeffrey Bland, PhD, FACN, FACB, considered the Father of Functional Medicine by many, states in an IMCJ article, “In the functional medicine model, the word function is aligned with the evolving understanding that disease is an endpoint and function is a process.” This is a significant distinction that illustrates the importance of connecting those molecular dots throughout your life and how your life journey resulted in your current state of health.

What can my biomarkers tell me?

The Institute for Human Optimization uses advanced biomarker and functional medicine testing to assess how an individual responds to personalized treatment for various health conditions. Providing precise, targeted therapy can be utilized to support physiological pathways and be used to enhance favorable gene expression to promote health and wellness.

We offer over one hundred advanced biomarker tests that can be used to optimize your health.

Here are some examples:

Next week, let's dive into all of the biomarkers and how my team can help you.

Until then, check this out.

To your longeivty,

Anil Bajnath MD
CEO/Founder, Institute for Human Optimization
Chief Medical Advisor, Longevity Insider HQ

*This content was provided by the Institute for Human Optimization (


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